ADGRA2
Sign in to saveAlso known as G protein-coupled receptor 124, TEM5, GPR124, adhesion G protein-coupled receptor A2
Probable G-protein coupled receptor 124 is a protein that in humans is encoded by the GPR124 gene. It is a member of the adhesion-GPCR family of receptors. Family members are characterized by an extended extracellular region with a variable number of protein domains coupled to a TM7 domain via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.
Gene data
ADGRA2- Name
- adhesion G protein-coupled receptor A2
- Type
- protein-coding
- Position
- 37,784,191–37,844,896 (+)
- Aliases
- GPR124, TEM5
- Ensembl
- ENSG00000020181
- RefSeq RNA
- NM_032777.10, XM_011544481.3, XM_011544482.3, XM_011544483.3, XM_054360257.1
- RefSeq protein
- NP_116166.9, XP_011542783.1, XP_011542784.1, XP_011542785.1, XP_054216232.1
Predicted to enable G protein-coupled receptor activity. Involved in positive regulation of canonical Wnt signaling pathway. Part of Wnt signalosome. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
adhesion G protein-coupled receptor A2
- Symbol
- ADGRA2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 8:37,784,191-37,844,896
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
3 sectionsContents
- Interactions
- References
- Further reading
Probable G-protein coupled receptor 124 is a protein that in humans is encoded by the GPR124 gene. It is a member of the adhesion-GPCR family of receptors. Family members are characterized by an extended extracellular region with a variable number of protein domains coupled to a TM7 domain via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.
== Interactions ==
Excerpted from Wikipedia’s “ADGRA2” article, available under the CC BY-SA 4.0 licence.