Structure via PubChem · Public domain (PubChem)
adinazolam
Sign in to saveAlso known as U-41123, 8-Chloro-1-((dimethylamino)methyl)-6-phenyl-4H-S-triazolo(4,3-a)(1,4)benzodiazepine, Adinazolamum
Adinazolam (marketed under the brand name Deracyn) is a tranquilizer of the triazolobenzodiazepine (TBZD) class, which are benzodiazepines (BZDs) fused with a triazole ring. It possesses anxiolytic, anticonvulsant, sedative, and antidepressant properties. Adinazolam was developed by Jackson B. Hester, who was seeking to enhance the antidepressant properties of alprazolam, which he also developed. Adinazolam was never FDA approved and never made available to the public market; however, it has been sold as a designer drug.
In the Vinony graph
Vinony's link graph records 689 inbound references to adinazolam, and connects out to benzodiazepine drug, validol and alphenal.
Vinony files it under Chloroarenes, Designer drugs and Drugboxes which contain changes to watched fields.
Vinony links it to 15 Wikipedia language editions.
Chemical data
- Formula
- C19H18ClN5
- Molecular weight
- 351.8 g/mol
- IUPAC name
- 1-(8-chloro-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-1-yl)-N,N-dimethylmethanamine
- SMILES
- CN(C)CC1=NN=C2N1C3=C(C=C(C=C3)Cl)C(=NC2)C4=CC=CC=C4
- InChIKey
- GJSLOMWRLALDCT-UHFFFAOYSA-N
- XLogP
- 1.6
- Polar surface area
- 46.3 Ų
- H-bond donors
- 0
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- anxiety
via ChEMBL · EBI
Research
120 papers- The open field as a paradigm to measure the effects of drugs on anxiety-like behaviors: a review.European journal of pharmacology · 2003
- Adinazolam, a Benzodiazepine-Type New Psychoactive Substance, Has Abuse Potential and Induces Withdrawal Symptoms in Rodents.ACS chemical neuroscience · 2023
- Pharmacological treatments in panic disorder in adults: a network meta-analysis.The Cochrane database of systematic reviews · 2023
- Pharmacokinetics, pharmacodynamics, and treatment issues of benzodiazepines: alprazolam, adinazolam, and clonazepam.Psychopharmacology bulletin · 1991
- Adinazolam-induced mania.The American journal of psychiatry · 1986
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 351.125
- Has use
- medication
Show 5 more facts
- chemical formula
- C₁₉H₁₈ClN₅
- canonical SMILES
- CN(C)CC1=NN=C2N1C3=C(C=C(C=C3)Cl)C(=NC2)C4=CC=CC=C4
- World Health Organisation international non-proprietary name
- adinazolam
- subject has role
- antidepressant
- Commons category
- Adinazolam
Sources (2)
via Wikidata · CC0
~12 min read
Encyclopedic overview
10 sectionsContents
- Use and purpose
- Availability
- Side effects
- Pharmacodynamics and pharmacokinetics
- Chemical information
- Reactivity
- Synthesis
- Metabolism
- See also
- References
Adinazolam (marketed under the brand name Deracyn) is a tranquilizer of the triazolobenzodiazepine (TBZD) class, which are benzodiazepines (BZDs) fused with a triazole ring. It possesses anxiolytic, anticonvulsant, sedative, and antidepressant properties. Adinazolam was developed by Jackson B. Hester, who was seeking to enhance the antidepressant properties of alprazolam, which he also developed. Adinazolam was never FDA approved and never made available to the public market; however, it has been sold as a designer drug.
== Use and purpose ==
Excerpted from Wikipedia’s “adinazolam” article, available under the CC BY-SA 4.0 licence.