AGTR1

Name

angiotensin II receptor type 1

Type

protein-coding

Position

148,697,784–148,743,045 (+)

Aliases

AG2S, AGTR1B, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, ATR1, HAT1R

Ensembl

ENSG00000144891

RefSeq RNA

NM_000685.5, NM_001382736.1, NM_001382737.1, NM_004835.5, NM_009585.4

RefSeq protein

NP_000676.1, NP_001369665.1, NP_001369666.1, NP_004826.6, NP_033611.1

Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2020].

via MyGene.info

Gene · Ensembl

angiotensin II receptor type 1

Symbol

AGTR1

Biotype

Protein coding

Organism

Homo sapiens

Location

3:148,697,784-148,743,045

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Image

Agtr1.png

via Wikidata · CC0