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AL-38022A

Structure via PubChem · Public domain (PubChem)

EntityQ12744507· pop 5· linked from 1,767 articles

AL-38022A is a serotonin receptor agonist and psychedelic drug of the indazolethylamine family related to the psychedelic tryptamine 5-MeO-AMT. It is one of a range of similar drugs developed for scientific research and with some possible clinical applications such as in the treatment of glaucoma. The drug acts as a potent and selective agonist for the 5-HT2 family of serotonin receptors, with highest binding affinity for the 5-HT2C subtype and around four times less affinity for 5-HT2A and 5-HT2B. In drug discrimination tests in animals, it fully substituted for the psychedelic drugs 5-MeO-DM

In the Vinony graph

Within Vinony's link graph, AL-38022A is referenced by 1,767 other articles, and connects out to tryptamines, N-methylserotonin and 5-methoxytryptamine.

It sits within the topics 5-HT2A agonists, 5-HT2B agonists and 5-HT2C agonists.

Its subject is documented across 4 Wikipedia language editions.

Chemical data

Formula
C13H17N3O
Molecular weight
231.29 g/mol
IUPAC name
1-(8,9-dihydro-7H-pyrano[2,3-g]indazol-1-yl)propan-2-amine
SMILES
CC(CN1C2=C(C=CC3=C2CCCO3)C=N1)N
InChIKey
FJRIVFVALIEIOY-UHFFFAOYSA-N
XLogP
1.4
Polar surface area
53.1 Ų
H-bond donors
1
H-bond acceptors
3
Formal charge
0

via PubChem

Wikidata facts

Mass
231.137162164
Show 3 more facts
chemical formula
C₁₃H₁₇N₃O
canonical SMILES
CC(CN1C2=C(C=CC3=C2CCCO3)C=N1)N
Commons category
AL-38022A

via Wikidata · CC0

~1 min read

Encyclopedic overview

3 sections
Contents
  • See also
  • References
  • External links

AL-38022A is a serotonin receptor agonist and psychedelic drug of the indazolethylamine family related to the psychedelic tryptamine 5-MeO-AMT. It is one of a range of similar drugs developed for scientific research and with some possible clinical applications such as in the treatment of glaucoma. The drug acts as a potent and selective agonist for the 5-HT2 family of serotonin receptors, with highest binding affinity for the 5-HT2C subtype and around four times less affinity for 5-HT2A and 5-HT2B. In drug discrimination tests in animals, it fully substituted for the psychedelic drugs 5-MeO-DMT and DOM. AL-38022A was first described in the scientific literature by Richard Glennon and colleagues in 2009.

==See also== Indazolethylamine Substituted tryptamine § Related compounds AL-34662 AL-37350A O-Methyl-AL-34662 Ro60-0175 VER-3323 YM-348

Excerpted from Wikipedia’s “AL-38022A” article, available under the CC BY-SA 4.0 licence.

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