tedatioxetine
Sign in to saveTedatioxetine (developmental code name Lu AA24530) is an experimental antidepressant developed by H. Lundbeck A/S for the treatment of major depressive disorder (MDD) and generalized anxiety disorder (GAD). It acts as a triple reuptake inhibitor (TRI) with preference for serotonin and norepinephrine over dopamine, and as an antagonist at 5-HT2A, 5-HT2C, 5-HT3, and α1A-adrenergic receptors. In 2007 Lundbeck and Takeda entered into a partnership that included tedatioxetine but was focused on another, more advanced Lundbeck drug candidate, vortioxetine.
In the Vinony graph
Within Vinony's link graph, tedatioxetine is referenced by 1,668 other articles, and connects out to propranolol, N-methylserotonin and histamine antagonist.
It is catalogued under topics including 4-Piperidinyl compounds, Abandoned drugs and Antidepressants.
Its subject is documented across 5 Wikipedia language editions.
Wikidata facts
- Mass
- 283.139
Show 3 more facts
- canonical SMILES
- CC1=CC=C(C=C1)SC2=CC=CC=C2C3CCNCC3
- Commons category
- Tedatioxetine
- chemical formula
- C₁₈H₂₁NS
Sources (2)
via Wikidata · CC0
~6 min read
Encyclopedic overview
8 sectionsContents
- Pharmacology
- Pharmacokinetics
- Pharmacodynamics
- Clinical development
- Synthesis
- See also
- References
- External links
{{Infobox drug | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 454958463 | IUPAC_name = 4-{2-[(4-methylphenyl)sulfanyl]phenyl}piperidine | image = Tedatioxetine.svg | image_class = skin-invert-image | width = 175 | image2 = Tedatioxetine ball-and-stick model.png | image_class2 = bg-transparent | width2 = 250
| tradename = | pregnancy_category = | legal_status = Investigational | routes_of_administration =
Excerpted from Wikipedia’s “tedatioxetine” article, available under the CC BY-SA 4.0 licence.