Structure via PubChem · Public domain (PubChem)
SB-215,505
Sign in to saveAlso known as SB-215505
SB-215505 is a drug which acts as a potent and selective antagonist at the serotonin 5-HT2B receptor, with good selectivity over the related 5-HT2A and 5-HT2C receptors. It is used in scientific research into the function of the 5-HT2 family of receptors, especially to study the role of 5-HT2B receptors in the heart, and to distinguish 5-HT2B-mediated responses from those produced by 5-HT2A or 5-HT2C.
Chemical data
- Formula
- C19H16ClN3O
- Molecular weight
- 337.8 g/mol
- IUPAC name
- 6-chloro-5-methyl-N-quinolin-4-yl-2,3-dihydroindole-1-carboxamide
- SMILES
- CC1=CC2=C(C=C1Cl)N(CC2)C(=O)NC3=CC=NC4=CC=CC=C43
- InChIKey
- BPVGSWDWIRIUME-UHFFFAOYSA-N
- XLogP
- 4
- Polar surface area
- 45.2 Ų
- H-bond donors
- 1
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 337.09819
Show 3 more facts
- Commons category
- SB-215,505
- chemical formula
- C₁₉H₁₆ClN₃O
- canonical SMILES
- CC1=C(C=C2C(=C1)CCN2C(=O)NC3=CC=NC4=CC=CC=C43)Cl
Sources (1)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
SB-215505 is a drug which acts as a potent and selective antagonist at the serotonin 5-HT2B receptor, with good selectivity over the related 5-HT2A and 5-HT2C receptors. It is used in scientific research into the function of the 5-HT2 family of receptors, especially to study the role of 5-HT2B receptors in the heart, and to distinguish 5-HT2B-mediated responses from those produced by 5-HT2A or 5-HT2C.
==References==
Excerpted from Wikipedia’s “SB-215,505” article, available under the CC BY-SA 4.0 licence.