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SB-215,505

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Also known as SB-215505

SB-215505 is a drug which acts as a potent and selective antagonist at the serotonin 5-HT2B receptor, with good selectivity over the related 5-HT2A and 5-HT2C receptors. It is used in scientific research into the function of the 5-HT2 family of receptors, especially to study the role of 5-HT2B receptors in the heart, and to distinguish 5-HT2B-mediated responses from those produced by 5-HT2A or 5-HT2C.

Wikidata facts

Mass
337.09819
Show 3 more facts
Commons category
SB-215,505
chemical formula
C₁₉H₁₆ClN₃O
canonical SMILES
CC1=C(C=C2C(=C1)CCN2C(=O)NC3=CC=NC4=CC=CC=C43)Cl
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via Wikidata · CC0

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Encyclopedic overview

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Contents
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SB-215505 is a drug which acts as a potent and selective antagonist at the serotonin 5-HT2B receptor, with good selectivity over the related 5-HT2A and 5-HT2C receptors. It is used in scientific research into the function of the 5-HT2 family of receptors, especially to study the role of 5-HT2B receptors in the heart, and to distinguish 5-HT2B-mediated responses from those produced by 5-HT2A or 5-HT2C.

==References==

Excerpted from Wikipedia’s “SB-215,505” article, available under the CC BY-SA 4.0 licence.

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