albaconazole

Chemical data

Formula

C20H16ClF2N5O2

Molecular weight

431.8 g/mol

IUPAC name

7-chloro-3-[(2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1,2,4-triazol-1-yl)butan-2-yl]quinazolin-4-one

SMILES

C[C@H]([C@](CN1C=NC=N1)(C2=C(C=C(C=C2)F)F)O)N3C=NC4=C(C3=O)C=CC(=C4)Cl

InChIKey

UHIXWHUVLCAJQL-MPBGBICISA-N

XLogP

2.5

Polar surface area

83.6 Ų

H-bond donors

1

H-bond acceptors

7

Formal charge

0

via PubChem

Drug data · ChEMBL

Max clinical phase

Phase 2

Molecule type

Small molecule

Indications

vulvovaginitis, tinea pedis, tinea unguium

via ChEMBL · EBI

• Albaconazole Polymeric Nanocapsules for Treating Trypanosoma cruzi Infections.Pathogens (Basel, Switzerland) · 2025
• Novel triazole antifungal drugs: focus on isavuconazole, ravuconazole and albaconazole.Current opinion in investigational drugs (London, England : 2000) · 2010
• Emerging azole antifungals.Expert opinion on emerging drugs · 2005
• Newer antifungal agents.Expert review of anti-infective therapy · 2011
• Activity of the new triazole derivative albaconazole against Trypanosoma (Schizotrypanum) cruzi in dog hosts.Antimicrobial agents and chemotherapy · 2004

via PubMed

Wikidata facts

Subclass of

chemical compound

Mass

431.096

via Wikidata · CC0