File:Amiodarone_structure.svg · Wikimedia Commons · See Wikimedia Commons
amiodarone
Sign in to saveAlso known as amiodarone hydrochloride, Cordarone®, 2-n-Butyl-3',5'-diiodo-4'-N-diethylaminoethoxy-3-benzoylbenzofuran, 2-Butyl-3-benzofuranyl 4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl ketone, 2-Butyl-3-(3,5-diiodo-4-(2-diethylaminoethoxy)benzoyl)benzofuran, Amiodaronum, Amiodarona
farmaco anti-aritmico usato in alcune tachiaritmie come la fibrillazione atriale e nella prevenzione delle tachicardie ventricolari ricorrenti
OverviewAI-generated
Amiodarone is a chemical compound with the formula C₂₅H₂₉I₂NO₃. Its IUPAC name is (2-butyl-1-benzofuran-3-yl)-[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]methanone. The substance has a mass of 645.024 and a weight of 645.3. It possesses a charge of 0, an xlogp value of 7.6, and a topological polar surface area of 42.7.
The molecule contains zero hydrogen bond donors and four hydrogen bond acceptors. Its canonical SMILES representation is CCCCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)I)OCCN(CC)CC)I. Amiodarone is referenced by 1,096 other encyclopedia articles. A search for the term amiodarone in PubMed yields 12,944 results.
Synthesized by Vinony from 17 facts across 4 sources: Wikidata, PubMed, PubChem, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.
Key facts
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 464394155
- Drug.image
- Amiodarone structure.svg
- Drug.image_class
- skin-invert-image
- Drug.image2
- Amiodarone-based-on-hydrochloride-xtal-3D-bs-17.png
- Drug.image_class2
- bg-transparent
- Drug.pronounce
- or
- Drug.tradename
- Cordarone, Nexterone, Pacerone, others
- Drug.MedlinePlus
- a687009
- Drug.DailyMedID
- Amiodarone
- Drug.pregnancy_AU
- C
- Drug.routes_of_administration
- By mouth, intravenous, intraosseous
- Drug.ATC_prefix
- C01
- Drug.ATC_suffix
- BD01
- Drug.legal_AU
- S4
- Drug.legal_CA
- Rx-only
- Drug.legal_US
- Rx-only
- Drug.bioavailability
- 20–55%
via Wikipedia infobox
Chemical data
- Formula
- C25H29I2NO3
- Molecular weight
- 645.3 g/mol
- IUPAC name
- (2-butyl-1-benzofuran-3-yl)-[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]methanone
- SMILES
- CCCCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)I)OCCN(CC)CC)I
- InChIKey
- IYIKLHRQXLHMJQ-UHFFFAOYSA-N
- XLogP
- 7.6
- Polar surface area
- 42.7 Ų
- H-bond donors
- 0
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1985
- Admin. routes
- oral, parenteral
- Indications
- atrial fibrillation, cardiomyopathy, congestive heart failure, heart failure
via ChEMBL · EBI
Research
12,944 papers- Acute Amiodarone Pulmonary Toxicity.Journal of cardiothoracic and vascular anesthesia · 2021
- Amiodarone-induced thyreopaties.Casopis lekaru ceskych · 2025
- Amiodarone.The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society · 1989
- Amiodarone and the thyroid.The American journal of medicine · 2005
- Amiodarone.The New England journal of medicine · 1987
via PubMed
Wikidata facts
- Mass
- 645.024
- Has use
- medication
Show 6 more facts
- significant drug interaction
- phenytoin
- Commons category
- Amiodarone
- chemical formula
- C₂₅H₂₉I₂NO₃
- medical condition treated
- ventricular tachycardia
- subject has role
- essential medicine
- canonical SMILES
- CCCCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)I)OCCN(CC)CC)I
via Wikidata · CC0
Article · Italiano
L'amiodarone è un farmaco anti-aritmico usato in alcune tachiaritmie come la fibrillazione atriale e nella prevenzione delle tachicardie ventricolari ricorrenti.
Abstract from DBpedia / Wikipedia · CC BY-SA