Ampakine
Sign in to save200px|thumb|right|class=skin-invert-image|CX-516, one of the earliest and a prototypical ampakine.
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It sits within the topics Ampakines and AMPA receptor positive allosteric modulators.
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Encyclopedic overview
8 sectionsContents
- Development
- Mechanism of action
- Side effects
- Medical applications
- See also
- References
- Further reading
- External links
200px|thumb|right|class=skin-invert-image|CX-516, one of the earliest and a prototypical ampakine.
Ampakines or AMPAkines are a subgroup of AMPA receptor positive allosteric modulators with a benzamide or closely related chemical structure. They are also known as "CX compounds". Ampakines take their name from the AMPA receptor (AMPAR), a type of ionotropic glutamate receptor with which the ampakines interact and act as positive allosteric modulators (PAMs) of. Although all ampakines are AMPAR PAMs, not all AMPAR PAMs are ampakines.
Excerpted from Wikipedia’s “Ampakine” article, available under the CC BY-SA 4.0 licence.