Ampakine
Sign in to save200px|thumb|right|class=skin-invert-image|CX-516, one of the earliest and a prototypical ampakine.
Article
8 sectionsContents
- Development
- Mechanism of action
- Side effects
- Medical applications
- See also
- References
- Further reading
- External links
200px|thumb|right|class=skin-invert-image|CX-516, one of the earliest and a prototypical ampakine.
Ampakines or AMPAkines are a subgroup of AMPA receptor positive allosteric modulators with a benzamide or closely related chemical structure. They are also known as "CX compounds". Ampakines take their name from the AMPA receptor (AMPAR), a type of ionotropic glutamate receptor with which the ampakines interact and act as positive allosteric modulators (PAMs) of. Although all ampakines are AMPAR PAMs, not all AMPAR PAMs are ampakines.