ANAPC1
Sign in to saveAlso known as APC1, MCPR, TSG24, anaphase promoting complex subunit 1
Anaphase-promoting complex subunit 1 is an enzyme that in humans is encoded by the ANAPC1 gene.
Gene data
ANAPC1- Name
- anaphase promoting complex subunit 1
- Type
- protein-coding
- Aliases
- APC1, MCPR, TSG24
This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation. [provided by RefSeq, Dec 2011].
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 7414
- exact match
- identifiers.org/ncbigene/64682
- genomic end
- 112642267
- genomic start
- 111611639
- cytogenetic location
- 2q13
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Article
4 sectionsContents
- Interactions
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Anaphase-promoting complex subunit 1 is an enzyme that in humans is encoded by the ANAPC1 gene.
ANAPC1 is one of at least ten subunits of the anaphase-promoting complex (APC), which functions at the metaphase-to-anaphase transition of the cell cycle and is regulated by spindle checkpoint proteins. The APC is an E3 ubiquitin ligase that targets cell cycle regulatory proteins for degradation by the proteasome, thereby allowing progression through the cell cycle (supplied by OMIM).