NACC1

Also known as BEND8, BTBD14B, BTBD30, NAC-1, NAC1, nucleus accumbens associated 1, NECFM

Nucleus accumbens-associated protein 1 is a protein that in humans is encoded by the NACC1 gene.

Gene data

NACC1

Name: nucleus accumbens associated 1
Type: protein-coding
Position: 13,116,468–13,141,147 (+)
Aliases: BEND8, BTBD14B, BTBD30, NAC-1, NAC1, NECFM
Ensembl: ENSG00000160877
RefSeq RNA: NM_052876.4, XM_005259721.4, XM_047438118.1, XM_054319689.1, XM_054319690.1
RefSeq protein: NP_443108.1, XP_005259778.1, XP_047294074.1, XP_054175664.1, XP_054175665.1

This gene encodes a member of the BTB/POZ protein family. BTB/POZ proteins are involved in several cellular processes including proliferation, apoptosis and transcription regulation. The encoded protein is a transcriptional repressor that plays a role in stem cell self-renewal and pluripotency maintenance. The encoded protein also suppresses transcription of the candidate tumor suppressor Gadd45GIP1, and expression of this gene may play a role in the progression of multiple types of cancer. A pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Feb 2012].