ای‌پی ۵

Also known as D-AP5, 5-phosphono-D-norvaline, (2R)-2-amino-5-phosphonopentanoic acid, APV, (2R)-2-amino-5-phosphovaleric acid

AP5 (also known as APV, '(2R)-amino-5-phosphonovaleric acid, or (2R)-amino-5-phosphonopentanoate') is a chemical compound used as a biochemical tool to study various cellular processes. It is a selective NMDA receptor antagonist that competitively inhibits the ligand (glutamate) binding site of NMDA receptors. AP5 blocks NMDA receptors in micromolar concentrations (~50 μM).