AQP9
Sign in to saveAlso known as AQP-9, HsT17287, SSC1, T17287, aquaporin 9
Aquaporin-9 (AQP-9) is a protein that in humans is encoded by the AQP9 gene.
Gene data
AQP9- Name
- aquaporin 9
- Type
- protein-coding
- Position
- 58,138,169–58,185,915 (+)
- Aliases
- AQP-9, HsT17287, SSC1, T17287
- Ensembl
- ENSG00000103569
- RefSeq RNA
- NM_001320635.2, NM_001320636.1, NM_020980.5
- RefSeq protein
- NP_001307564.1, NP_001307565.1, NP_066190.2
The aquaporins are a family of water-selective membrane channels. This gene encodes a member of a subset of aquaporins called the aquaglyceroporins. This protein allows passage of a broad range of noncharged solutes and also stimulates urea transport and osmotic water permeability. This protein may also facilitate the uptake of glycerol in hepatic tissue . The encoded protein may also play a role in specialized leukocyte functions such as immunological response and bactericidal activity. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
aquaporin 9
- Symbol
- AQP9
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 15:58,138,169-58,185,915
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- found in taxon
- Homo sapiens
- HomoloGene ID
- 41405
- exact match
- identifiers.org/ncbigene/366
- chromosome
- human chromosome 15
- genomic start
- 58430368
- genomic end
- 58478110
- cytogenetic location
- 15q21.3
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- Further reading
- External links
Aquaporin-9 (AQP-9) is a protein that in humans is encoded by the AQP9 gene.
The aquaporins/major intrinsic protein are a family of water-selective membrane channels. Aquaporin-9 has greater sequence similarity with AQP3 and AQP7 and they may be a subfamily. Aquaporin-9 allows passage of a wide variety of noncharged solutes. AQP-9 stimulates urea transport and osmotic water permeability; there are contradicting reports about its role in providing glycerol permeability. Aquaporin-9 may also have some role in specialized leukocyte functions such as immunological response and bactericidal activity.
Excerpted from Wikipedia’s “AQP9” article, available under the CC BY-SA 4.0 licence.