ARAF
Sign in to saveAlso known as A-Raf proto-oncogene, serine/threonine kinase, A-RAF, ARAF1, PKS2, RAFA1, Serine/threonine-protein kinase A-Raf
gene umano
Gene data
ARAF- Name
- A-Raf proto-oncogene, serine/threonine kinase
- Type
- protein-coding
- Chromosome
- X
- Position
- 47,561,043–47,571,921 (+)
- Aliases
- A-RAF, ARAF1, PKS2, RAFA1
- Ensembl
- ENSG00000078061
- RefSeq RNA
- NM_001256196.2, NM_001256197.2, NM_001654.5
- RefSeq protein
- NP_001243125.1, NP_001243126.1, NP_001645.1
This proto-oncogene belongs to the RAF subfamily of the Ser/Thr protein kinase family, and maybe involved in cell growth and development. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2012]
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
MAPK signaling pathway - Homo sapiens (human)ErbB signaling pathway - Homo sapiens (human)FoxO signaling pathway - Homo sapiens (human)Vascular smooth muscle contraction - Homo sapiens (human)Natural killer cell mediated cytotoxicity - Homo sapiens (human)Long-term potentiation - Homo sapiens (human)Serotonergic synapse - Homo sapiens (human)Long-term depression - Homo sapiens (human)Regulation of actin cytoskeleton - Homo sapiens (human)Insulin signaling pathway - Homo sapiens (human)
via MyGene.info
Gene · Ensembl
A-Raf proto-oncogene, serine/threonine kinase
- Symbol
- ARAF
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- Chr X:47,561,043-47,571,921
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein ARAF PDB 1wxm.png
Show 7 more facts
- HomoloGene ID
- 1249
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/369
- genomic start
- 47561205
- genomic end
- 47571908
- chromosome
- human X chromosome
- cytogenetic location
- Xp11.3
via Wikidata · CC0