benactyzine
Sign in to saveAlso known as Methylbenactyzium Bromide, EA-2092
Benactyzine is an anticholinergic drug that was used in the treatment of clinical depression and anxiety disorders before it was pulled from the U.S. market by the FDA due to serious side effects.
Research
719 papers- Benactyzine.Antibiotic medicine & clinical therapy (New York, NY) · 1958
- Synthesis and preliminary biological evaluation of gabactyzine, a benactyzine-GABA mutual prodrug, as an organophosphate antidote.Scientific reports · 2022
- Benactyzine metabolism in the rat.Archives internationales de pharmacodynamie et de therapie · 1970
- [Benactyzine in pediatrics].Prensa medica argentina · 1958
- Benactyzine as an aid in treatment of anxiety states; preliminary report.British medical journal · 1957
via PubMed
Wikidata facts
- Mass
- 327.183444
Show 3 more facts
- chemical formula
- C₂₀H₂₅NO₃
- canonical SMILES
- CCN(CC)CCOC(=O)C(C1=CC=CC=C1)(C2=CC=CC=C2)O
- Commons category
- Benactyzine
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- History
- See also
- References
- External links
Benactyzine is an anticholinergic drug that was used in the treatment of clinical depression and anxiety disorders before it was pulled from the U.S. market by the FDA due to serious side effects.
Its use for these indications was limited by side effects such as dry mouth and nausea, and at high doses it can cause more severe symptoms such as deliriant and hallucinogenic effects. "Large doses of benactyzine in normal subjects may produce a state resembling the action of mescaline or LSD."