Structure via PubChem · Public domain (PubChem)
mepenzolate
Sign in to saveAlso known as Mepenzolic acid
Mepenzolate is an antimuscarinic medication primarily used to treat peptic ulcers by reducing stomach acid secretion. It is the methylated version of N-methyl-3-piperidyl benzilate.
Chemical data
- Formula
- C21H26NO3+
- Molecular weight
- 340.4 g/mol
- IUPAC name
- (1,1-dimethylpiperidin-1-ium-3-yl) 2-hydroxy-2,2-diphenylacetate
- SMILES
- C[N+]1(CCCC(C1)OC(=O)C(C2=CC=CC=C2)(C3=CC=CC=C3)O)C
- InChIKey
- GKNPSSNBBWDAGH-UHFFFAOYSA-N
- XLogP
- 3.2
- Polar surface area
- 46.5 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 1
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1956
- Admin. routes
- oral
- Indications
- gastrointestinal disease
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 340.191269
- Has use
- medication
Show 3 more facts
- canonical SMILES
- C[N+]1(CCCC(C1)OC(=O)C(C2=CC=CC=C2)(C3=CC=CC=C3)O)C
- defined daily dose
- 0.1
- chemical formula
- C₂₁H₂₆NO₃⁺
Sources (3)
via Wikidata · CC0
~2 min read
Encyclopedic overview
5 sectionsContents
- Pharmacology
- Chemical structure
- Clinical Uses
- Side Effects
- References
Mepenzolate is an antimuscarinic medication primarily used to treat peptic ulcers by reducing stomach acid secretion. It is the methylated version of N-methyl-3-piperidyl benzilate.
== Pharmacology == Mepenzolate works by blocking the action of acetylcholine on muscarinic receptors in the gastrointestinal tract. This action reduces the secretion of stomach acid and slows intestinal motility, making it useful in the management of peptic ulcers and other gastrointestinal disorders.
Excerpted from Wikipedia’s “mepenzolate” article, available under the CC BY-SA 4.0 licence.