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imolamine
Sign in to saveImolamine (INN, BAN; brand names Angolon, Angoril, Circuline, Irri-Cor, Irrigor, Coremax) is a coronary vasodilator which is used in the treatment of angina pectoris and as a local anesthetic.
Chemical data
- Formula
- C14H20N4O
- Molecular weight
- 260.33 g/mol
- IUPAC name
- N,N-diethyl-2-(5-imino-3-phenyl-1,2,4-oxadiazol-4-yl)ethanamine
- SMILES
- CCN(CC)CCN1C(=NOC1=N)C2=CC=CC=C2
- InChIKey
- MGSPDRWOUCPKNZ-UHFFFAOYSA-N
- XLogP
- 2.5
- Polar surface area
- 51.9 Ų
- H-bond donors
- 1
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- cardiovascular disease
via ChEMBL · EBI
Research
15 papers- [The effects of imolamine on auriculo-ventricular conduction by recoil of His potential].Archives internationales de pharmacodynamie et de therapie · 1975
- [Imolamine in acute coronary insufficiency. Some considerations in the light of 30 treated cases].La Clinica terapeutica · 1977
- [Imolamine in myocardial infarct: various considerations on 34 treated cases].La Clinica terapeutica · 1976
- [Imolamine in ischemic cardiopathy: results of a study of platelet aggregation in vitro and ex vivo].La Clinica terapeutica · 1980
- [Haemodynamic effects of imolamine (author's transl)].Annales de cardiologie et d'angeiologie · 1978
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 260.164
- Has use
- medication
Show 5 more facts
- chemical formula
- C₁₄H₂₀N₄O
- canonical SMILES
- CCN(CC)CCN1C(=NOC1=N)C2=CC=CC=C2
- defined daily dose
- 90
- subject has role
- vasodilator agent
- Commons category
- Imolamine
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- Synthesis
- References
Imolamine (INN, BAN; brand names Angolon, Angoril, Circuline, Irri-Cor, Irrigor, Coremax) is a coronary vasodilator which is used in the treatment of angina pectoris and as a local anesthetic.
Use patents:
Excerpted from Wikipedia’s “imolamine” article, available under the CC BY-SA 4.0 licence.