BICD1

Also known as BICD, BICD cargo adaptor 1, bic-D 1

Bicaudal D cargo adaptor 1 is a protein that in humans is encoded by the BICD1 gene.

In the Vinony graph

Within Vinony's link graph, BICD1 is referenced by 4 other articles, and connects out to PubMed, human chromosome 12 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 12.

Its subject is documented across 5 Wikipedia language editions.

Gene data

BICD1

Name: BICD cargo adaptor 1
Type: protein-coding
Position: 32,106,643–32,383,633 (+)
Aliases: BICD, bic-D 1
Ensembl: ENSG00000151746
RefSeq RNA: NM_001003398.3, NM_001354186.2, NM_001354187.2, NM_001354188.2, NM_001354189.2
RefSeq protein: NP_001003398.1, NP_001341115.1, NP_001341116.1, NP_001341117.1, NP_001341118.1

This gene encodes an adaptor protein that belongs to the bicaudal D family of dynein cargo adaptors. The encoded protein acts as an intracellular cargo transport cofactor that regulates the microtubule-based loading of cargo onto the dynein motor complex. It also controls dynein motor activity and coordination. It has a domain architecture consisting of coiled-coil domains at the N- and C-termini that are highly conserved in other family members. Naturally occurring mutations in this gene are associated with short telomere length and emphysema. [provided by RefSeq, Aug 2017].