bioinformatics
Sign in to save500px|thumbnail|right|Early bioinformatics—computational alignment of experimentally determined sequences of a class of related proteins; see for further information. thumbnail|220px|Map of the human X chromosome (from the National Center for Biotechnology Information (NCBI) website) Bioinformatics () is an interdisciplinary field of science that develops computational methods and software tools for understanding biological data, especially when the data sets are large and complex. Bioinformatics integrates principles from biology, chemistry, physics, computer science, data science, computer p
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Bioinformatics is an interdisciplinary field that uses computational methods and software tools to understand biological data, particularly when working with large and complex datasets. It combines principles from biology, chemistry, physics, computer science, and data science to help researchers make sense of biological information.
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43 sectionsContents
- History
- Sequences
- Goals
- Sequence analysis
- DNA sequencing
- Sequence assembly
- Genome annotation
- Gene function prediction
- Computational evolutionary biology
- Comparative genomics
- Pan genomics
- Genetics of disease
- Analysis of mutations in cancer
- Gene and protein expression
- Analysis of gene expression
- Analysis of protein expression
- Analysis of regulation
- Analysis of cellular organization
- Microscopy and image analysis
- Protein localization
- Nuclear organization of chromatin
- Amino acid sequence
- Homology
- Network and systems biology
- Molecular interaction networks
- Biodiversity informatics
- Others
- Literature analysis
- High-throughput image analysis
- High-throughput single cell data analysis
- Ontologies and data integration
- Databases
- Software and tools
- Open-source bioinformatics software
- Web services in bioinformatics
- Bioinformatics workflow management systems
- BioCompute and BioCompute Objects
- Education platforms
- Conferences
- See also
- References
- Further reading
- External links
500px|thumbnail|right|Early bioinformatics—computational alignment of experimentally determined sequences of a class of related proteins; see for further information. thumbnail|220px|Map of the human X chromosome (from the National Center for Biotechnology Information (NCBI) website) Bioinformatics () is an interdisciplinary field of science that develops computational methods and software tools for understanding biological data, especially when the data sets are large and complex. Bioinformatics integrates principles from biology, chemistry, physics, computer science, data science, computer programming, information engineering, mathematics, and statistics to analyze and interpret biological data. This process can sometimes be referred to as computational biology; however, the distinction between the two terms is often disputed. The term computational biology refers to building and using models of biological systems.
Computational, statistical, and computer programming techniques have been used for computer simulation analyses of biological queries. They include reused specific analysis "pipelines", particularly in the field of genomics, such as by the identification of genes and single nucleotide polymorphisms (SNPs). These pipelines are used to better understand the genetic basis of disease, unique adaptations, desirable properties (especially in agricultural species), or differences between populations. Bioinformatics also includes proteomics, which aims to understand the organizational principles within nucleic acid and protein sequences.