Structure via PubChem · Public domain (PubChem)
biperiden
Sign in to saveAlso known as Akineton®, alpha-5-norbornen-2-yl-alpha-phenyl-1-piperidinepropanol, alpha-bicyclo[2.2.1]hept-5-en-2-yl-alpha-phenyl-1-piperidinepropanol, Beperiden, alpha-Bicyclo[2.2.1]hept-5-en-2-yl-alpha-phenyl-1-piperidinepropanol, Biperidene, 1-Bicyclo[2.2.1]hept-5-en-2-yl-1-phenyl-3-piperidin-1-yl-propan-1-ol
Biperiden, sold under the brand name Akineton among others, is a medication used to treat Parkinson disease, certain drug-induced movement disorders and Tourette Syndrome. It is not recommended for tardive dyskinesias. It is taken by mouth, injection into a vein, or muscle.
Chemical data
- Formula
- C21H29NO
- Molecular weight
- 311.5 g/mol
- IUPAC name
- 1-(2-bicyclo[2.2.1]hept-5-enyl)-1-phenyl-3-piperidin-1-ylpropan-1-ol
- SMILES
- C1CCN(CC1)CCC(C2CC3CC2C=C3)(C4=CC=CC=C4)O
- InChIKey
- YSXKPIUOCJLQIE-UHFFFAOYSA-N
- XLogP
- 4.3
- Polar surface area
- 23.5 Ų
- H-bond donors
- 1
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Research
786 papers- Biperiden.2006
- Biperiden.2012
- Drug Efficacy in the Treatment of Antipsychotic-Induced Akathisia: A Systematic Review and Network Meta-Analysis.JAMA network open · 2024
- Biperiden-Induced Delirium In A Five-Years Old Child.Current drug safety · 2019
- Biperiden reverses the increase in 50-kHz ultrasonic vocalizations but not the increase in locomotor activity induced by cocaine.Behavioural brain research · 2024
via PubMed
~7 min read
Encyclopedic overview
14 sectionsContents
- Medical uses
- Pregnancy and lactation
- Children
- Contraindications
- Side effects
- Interactions
- Overdose
- Pharmacology
- Pharmacodynamics
- Anticholinergic activity
- Other actions
- Pharmacokinetics
- History
- References
Biperiden, sold under the brand name Akineton among others, is a medication used to treat Parkinson disease, certain drug-induced movement disorders and Tourette Syndrome. It is not recommended for tardive dyskinesias. It is taken by mouth, injection into a vein, or muscle.
Common side effects include blurred vision, dry mouth, sleepiness, constipation, and confusion. It should not be used in people with a bowel obstruction or glaucoma. It is unclear if use in pregnancy or breastfeeding is safe. Biperiden is in the anticholinergic family of medication.
Excerpted from Wikipedia’s “biperiden” article, available under the CC BY-SA 4.0 licence.