Gene data
BIRC6- Name
- baculoviral IAP repeat containing 6
- Type
- protein-coding
- Position
- 32,357,019–32,619,582 (+)
- Aliases
- APOLLON, BRUCE
- Ensembl
- ENSG00000115760
- RefSeq RNA
- NM_001378125.1, NM_001446552.1, NM_001446553.1, NM_016252.4, XM_005264450.5
- RefSeq protein
- NP_001365054.1, NP_001433481.1, NP_001433482.1, NP_057336.3, XP_005264507.2
This gene encodes a protein with a BIR (baculoviral inhibition of apoptosis protein repeat) domain and a UBCc (ubiquitin-conjugating enzyme E2, catalytic) domain. This protein inhibits apoptosis by facilitating the degradation of apoptotic proteins by ubiquitination. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
Ubiquitin mediated proteolysis - Homo sapiens (human)Apoptosis - multiple species - Homo sapiens (human)DiseaseDiseases of signal transduction by growth factor receptors and second messengersSignaling by ALK in cancerALK mutants bind TKIsSignaling by ALK fusions and activated point mutantsApoptosis Modulation and Signaling
via MyGene.info
Gene · Ensembl
baculoviral IAP repeat containing 6
- Symbol
- BIRC6
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:32,357,019-32,619,582
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 7248
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/57448
- genomic end
- 32618878
- genomic start
- 32357023
- chromosome
- human chromosome 2
- cytogenetic location
- 2p22.3
Sources (3)
via Wikidata · CC0