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GeneQ18037206· pop 10· linked from 38 articles

Also known as CAP, HUNK1, HUNKI, MCAP, bromodomain containing 4

Gen der Spezies Homo sapiens

Gene data

BRD4
Name
bromodomain containing 4
Type
protein-coding
Position
15,235,519–15,332,547 (−)
Aliases
CAP, CDLS6, FSHRG4, HUNK1, HUNKI, MCAP
RefSeq RNA
NM_001330384.2, NM_001379291.1, NM_001379292.1, NM_014299.3, NM_058243.3
RefSeq protein
NP_001317313.1, NP_001366220.1, NP_001366221.1, NP_055114.1, NP_490597.1

The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

bromodomain containing 4

Symbol
BRD4
Biotype
Protein coding
Organism
Homo sapiens
Location
19:15,235,519-15,332,547
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Image
Protein BRD4 PDB 2oss.png
Show 8 more facts
HomoloGene ID
137685
found in taxon
Homo sapiens
genomic end
15443356
genomic start
15347647
cytogenetic location
19p13.12
expressed in
vena cava
Sources (6)

via Wikidata · CC0