Structure via PubChem · Public domain (PubChem)
bromopride
Sign in to saveAlso known as 4-amino-5-bromo-N-[2-(diethylamino)ethyl]-2-methoxybenzamide, Bromoprid, Bromoprida, Bromopridum
Bromopride (INN) is a dopamine antagonist with prokinetic properties widely used as an antiemetic, closely related to metoclopramide. It is not available in the United States.
Chemical data
- Formula
- C14H22BrN3O2
- Molecular weight
- 344.25 g/mol
- IUPAC name
- 4-amino-5-bromo-N-[2-(diethylamino)ethyl]-2-methoxybenzamide
- SMILES
- CCN(CC)CCNC(=O)C1=CC(=C(C=C1OC)N)Br
- InChIKey
- GIYAQDDTCWHPPL-UHFFFAOYSA-N
- XLogP
- 2.8
- Polar surface area
- 67.6 Ų
- H-bond donors
- 2
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 3
- Molecule type
- Small molecule
- Indications
- dyspepsia, gastrointestinal disease
via ChEMBL · EBI
Research
78 papers- Bromopride stimulates 5-HT(4)-serotonin receptors in the human atrium.Naunyn-Schmiedeberg's archives of pharmacology · 2025
- Population pharmacokinetics of orally administrated bromopride: Focus on the absorption process.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences · 2020
- Bromopride, metoclopramide, or ondansetron for the treatment of vomiting in the pediatric emergency department: a randomized controlled trial.Jornal de pediatria · 2018
- Development of novel montmorillonite-based sustained release system for oral bromopride delivery.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences · 2022
- Differential effects of bromopride and domperidone on cholinesterase activity in rat tissues.Life sciences · 1995
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 343.089539
- Has use
- medication
Show 8 more facts
- subject has role
- antiemetic
- chemical formula
- C₁₄H₂₂BrN₃O₂
- MCN code
- 2924.29.51
- route of administration
- intravenous infusion and defusion
- canonical SMILES
- CCN(CC)CCNC(=O)C1=CC(=C(C=C1OC)N)Br
- medical condition treated
- indigestion
- Commons category
- Bromopride
- defined daily dose
- 20
via Wikidata · CC0
~1 min read
Encyclopedic overview
5 sectionsContents
- Indications
- Adverse effects
- Chemistry
- Availability
- References
Bromopride (INN) is a dopamine antagonist with prokinetic properties widely used as an antiemetic, closely related to metoclopramide. It is not available in the United States.
Bromopride appears to be safe and effective for use in pregnancy.
Excerpted from Wikipedia’s “bromopride” article, available under the CC BY-SA 4.0 licence.