C3AR1
Sign in to saveAlso known as AZ3B, C3AR, HNFAG09, complement component 3a receptor 1, complement C3a receptor 1
protein-coding gene in the species Homo sapiens
Gene data
C3AR1- Name
- complement C3a receptor 1
- Type
- protein-coding
- Position
- 8,056,844–8,066,374 (−)
- Aliases
- AZ3B, C3AR, HNFAG09
- Ensembl
- ENSG00000171860
- RefSeq RNA
- NM_001326475.2, NM_001326477.2, NM_004054.4
- RefSeq protein
- NP_001313404.1, NP_001313406.1, NP_004045.1
C3a is an anaphylatoxin released during activation of the complement system. The protein encoded by this gene is an orphan G protein-coupled receptor for C3a. Binding of C3a by the encoded receptor activates chemotaxis, granule enzyme release, superoxide anion production, and bacterial opsonization. [provided by RefSeq, May 2016].
Gene Ontology
Biological process
Molecular function
complement receptor activitycomplement component C3a receptor activitycomplement component C3a receptor activitycomplement component C3a receptor activitycomplement component C3a receptor activitycomplement component C5a receptor activityG protein-coupled receptor activityG protein-coupled receptor activity
Pathways
Neuroactive ligand-receptor interaction - Homo sapiens (human)Complement and coagulation cascades - Homo sapiens (human)Staphylococcus aureus infection - Homo sapiens (human)Coronavirus disease - COVID-19 - Homo sapiens (human)Signal TransductionDiseaseComplement cascadeInnate Immune SystemImmune SystemSignaling by GPCR
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 2992
- exact match
- identifiers.org/ncbigene/719
- genomic end
- 8066359
- genomic start
- 8056844
- cytogenetic location
- 12p13.31
Sources (3)
via Wikidata · CC0
Connections
Q180686
Entity
human chromosome 12
Entity
Ensembl genome database project
Entity
C3
Gene
complement component 4
Entity
Wikidata
Entity
gene
Entity
chromosome
Entity
digital object identifier
Entity
inflammation
Entity
pheromone
Entity
bibcode
Entity
human genome
Entity
Q229883
Entity
base pair
Entity
locus
Entity
Medical Subject Headings
Entity
gene expression
Entity
complement system
Entity
Online Mendelian Inheritance in Man
Entity