Skip to content
EntityQ182517· pop 18· linked from 66 articles

Also known as CA 19-9, carbohydrate antigen 19-9, cancer antigen 19-9, sialylated Lewis (a) antigen, Carbohydrate antigen 19-9, CA-19-9 Antigen, alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-L-Fuc-(1->4)]-D-GlcNAc, NeuAcalpha2,3Galbeta1-3[Fucalpha1-4]GlcNAc

Carbohydrate antigen 19-9 (CA19-9), also known as sialyl-LewisA, is a tetrasaccharide which is usually attached to O-glycans on the surface of cells. It is known to play a role in cell-to-cell recognition processes. It is also a tumor marker used primarily in the management of pancreatic cancer.

Research

9,811 papers

via PubMed

~2 min read

Encyclopedic overview

8 sections
Contents
  • Structure
  • Clinical significance
  • Tumor marker
  • Limitations
  • History
  • See also
  • References
  • External links

Carbohydrate antigen 19-9 (CA19-9), also known as sialyl-LewisA, is a tetrasaccharide which is usually attached to O-glycans on the surface of cells. It is known to play a role in cell-to-cell recognition processes. It is also a tumor marker used primarily in the management of pancreatic cancer.

==Structure== CA19-9 is the sialylated form of Lewis antigenA. It is a tetrasaccharide with the sequence Neu5Acα2-3Galβ1-3[Fucα1-4]GlcNAcβ.

Excerpted from Wikipedia’s “CA19-9” article, available under the CC BY-SA 4.0 licence.