carglumic acid

Also known as N-carbamylglutamate, OE-312, (2S)-2-(carbamoylamino)pentanedioic acid, (S)-2-ureidopentanedioic acid, carbamylglutamic acid, ureidoglutaric acid, L-N-carbamoylglutamic acid, carbamino-L-glutamic acid

chemical compound

Chemical data

Formula: C6H10N2O5
Molecular weight: 190.15 g/mol
IUPAC name: (2S)-2-(carbamoylamino)pentanedioic acid
SMILES: C(CC(=O)O)[C@@H](C(=O)O)NC(=O)N
InChIKey: LCQLHJZYVOQKHU-VKHMYHEASA-N
XLogP: -2.4
Polar surface area: 130 Å²
H-bond donors: 4
H-bond acceptors: 5
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Approved
Molecule type: Small molecule
First approval: 2003
Admin. routes: oral
Indications: Hyperammonemia due to N-acetylglutamate synthetase deficiency, Hyperammonemia, propionic acidemia, inborn errors of metabolism

via ChEMBL · EBI

Wikidata facts

Has part: oxygen
Mass: 190.058971
Has use: medication

Show 6 more facts

chemical formula: C₆H₁₀N₂O₅
canonical SMILES: C(CC(=O)O)C(C(=O)O)NC(=O)N
isomeric SMILES: C(CC(=O)O)[C@@H](C(=O)O)NC(=O)N
World Health Organisation international non-proprietary name: carglumic acid
defined daily dose: 0.2
found in taxon: Caenorhabditis elegans

Sources (4)

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