carmustine

Also known as BiCNU®, Carustine®, N,N'-Bis(2-chloroethyl)-N-nitrosourea, Gliadel, Bicnu (TN), Bischloroethyl nitrosourea, BCNU

Carmustine, sold under the brand name BiCNU among others, is a medication used mainly for chemotherapy. It is a nitrogen mustard β-chloro-nitrosourea compound used as an alkylating agent.

Key facts

Drug.tradename: BiCNU, Gliadel
Drug.MedlinePlus: a682060
Drug.DailyMedID: Carmustine
Drug.class: Antineoplastic agents

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Chemical data

Formula: C5H9Cl2N3O2
Molecular weight: 214.05 g/mol
IUPAC name: 1,3-bis(2-chloroethyl)-1-nitrosourea
SMILES: C(CCl)NC(=O)N(CCCl)N=O
InChIKey: DLGOEMSEDOSKAD-UHFFFAOYSA-N
XLogP: 1.5
Polar surface area: 61.8 Å²

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Article

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Contents

Description
Mechanism of action
Uses
Implants
Production
See also
References
External links

Carmustine, sold under the brand name BiCNU among others, is a medication used mainly for chemotherapy. It is a nitrogen mustard β-chloro-nitrosourea compound used as an alkylating agent.

==Description== Carmustine is an orange-yellow solid medication used mainly for chemotherapy. It is a nitrogen mustard β-chloro-nitrosourea compound.