CD32 (cluster of differentiation 32), also known as FcγRII or FCGR2, is a surface receptor glycoprotein belonging to the Ig gene superfamily. CD32 can be found on the surface of a variety of immune cells. CD32 has a low-affinity for the Fc region of IgG antibodies in monomeric form, but high affinity for IgG immune complexes. CD32 has two major functions: cellular response regulation, and the uptake of immune complexes. Cellular responses regulated by CD32 include phagocytosis, cytokine stimulation, and endocytic transport. Dysregulated CD32 is associated with different forms of autoimmunity,
Il CD32 è una glicoproteina di membrana presente sui linfociti B e sui macrofagi. Il suo nome FCγRII è indicativo della sua funzione ovvero recettore per la parte costante delle immunoglobuline di tipo γ con affinità intermedia (mentre ha affinità alta e bassa).
Abstract from DBpedia / Wikipedia · CC BY-SA
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).