CD1b molecule
Sign in to saveAlso known as CD1B antigen, b polypeptide, differentiation antigen CD1-alpha-3, CD1B, T-cell surface glycoprotein CD1b, cortical thymocyte antigen CD1B
T-cell surface glycoprotein CD1b is a protein that in humans is encoded by the CD1B gene.
Protein · UniProt
T-cell surface glycoprotein CD1b
- Gene
- CD1B
- Organism
- Homo sapiens (Human)
- Length
- 333 aa
- Molecular mass
- 36,939 Da
- Evidence
- 1: Evidence at protein level
Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells
Swiss-Prot (reviewed) · via UniProt
~3 min read
Encyclopedic overview
5 sectionsContents
- Structure and function
- Clinical significance
- References
- Further reading
- External links
T-cell surface glycoprotein CD1b is a protein that in humans is encoded by the CD1B gene.
CD1b belongs to group 1 of CD1 family of transmembrane glycoproteins. CD1 molecules are expressed on the surface of numerous different human antigen presenting cells (DCs, monocytes and some thymocytes). This specialised group of glycoproteins present self and non-self lipid-based antigens to specific αβ T-cells. CD1 molecules are structurally related to the major histocompatibility complex (MHC), belonging to MHC class I-like genes. The human CD1 locus is found on chromosome 1 and contains five nonpolymorphic genes (CD1a, CD1b, CD1c, CD1d and CD1e).
Excerpted from Wikipedia’s “CD1b molecule” article, available under the CC BY-SA 4.0 licence.