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ProteinQ21113034· pop 10· linked from 360 articles

CD6 molecule

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Also known as CD6, TP120, CD6 antigen, T-cell differentiation antigen CD6, T12

CD6 (Cluster of Differentiation 6) is a human protein encoded by the gene.

In the Vinony graph

Within Vinony's link graph, CD6 molecule is referenced by 360 other articles, and connects out to PubMed, T-lymphocytes and Ensembl genome database project.

It is catalogued under topics including Clusters of differentiation and Genes on human chromosome 11.

Its subject is documented across 10 Wikipedia language editions.

Protein · UniProt

T-cell differentiation antigen CD6

Gene
CD6
Organism
Homo sapiens (Human)
Length
668 aa
Molecular mass
71,801 Da
Evidence
1: Evidence at protein level

Cell adhesion molecule that mediates cell-cell contacts and regulates T-cell responses via its interaction with ALCAM/CD166 (PubMed:15048703, PubMed:15294938, PubMed:16352806, PubMed:16914752, PubMed:24584089, PubMed:24945728). Contributes to signaling cascades triggered by activation of the TCR/CD3 complex (PubMed:24584089). Functions as a costimulatory molecule; promotes T-cell activation and proliferation (PubMed:15294938, PubMed:16352806, PubMed:16914752). Contributes to the formation and maturation of the immunological synapse (PubMed:15294938, PubMed:16352806). Functions as a calcium-…

3D-structureAdaptive immunityAlternative splicingCell adhesionCell membraneDisulfide bondGlycoproteinImmunity
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Swiss-Prot (reviewed) · via UniProt

Wikidata facts

Instance of
protein
Show 3 more facts
biological process
endocytosis
found in taxon
Homo sapiens
Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

6 sections
Contents
  • Function
  • Clinical significance
  • See also
  • References
  • Further reading
  • External links

CD6 (Cluster of Differentiation 6) is a human protein encoded by the gene.

== Function ==

Excerpted from Wikipedia’s “CD6 molecule” article, available under the CC BY-SA 4.0 licence.

Available in 10 languages

via Wikidata sitelinks · CC0

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