CEP192
Sign in to saveAlso known as PPP1R62, centrosomal protein 192
Centrosomal protein of 192 kDa, also known as Cep192, is a protein that in humans is encoded by the CEP192 gene. It is the homolog of the C. elegans and D. melanogaster gene SPD-2.
Gene data
CEP192- Name
- centrosomal protein 192
- Type
- protein-coding
- Aliases
- PPP1R62
Enables phosphatase binding activity. Involved in centrosome-templated microtubule nucleation; mitotic spindle assembly; and protein localization to centrosome. Located in centriole; centrosome; and cytosol. [provided by Alliance of Genome Resources, Apr 2022]
via MyGene.info
Gene · Ensembl
centrosomal protein 192
- Symbol
- CEP192
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 18:12,991,283-13,125,053
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 73526
- exact match
- identifiers.org/ncbigene/55125
- genomic end
- 13125051
- genomic start
- 12991361
- cytogenetic location
- 18p11.21
Sources (3)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- References
- External links
- Further reading
Centrosomal protein of 192 kDa, also known as Cep192, is a protein that in humans is encoded by the CEP192 gene. It is the homolog of the C. elegans and D. melanogaster gene SPD-2.
Cep192 is a major regulator of pericentriolar material recruitment, centrosome maturation, and centriole duplication in mammalian cells. It stimulates the formation of the scaffolding upon which gamma tubulin ring complexes and other proteins involved in microtubule nucleation and spindle assembly become functional during mitosis.