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GeneQ18036574· pop 5· linked from 34 articles

Also known as NPHP15, centrosomal protein 164

Centrosomal protein of 164 kDa, also known as CEP164, is a protein that in humans is encoded by the CEP164 gene. Its function appears two be twofold: CEP164 is required for primary cilium formation. Furthermore, it is an important component in the response to DNA damage by UV light.

Gene data

CEP164
Name
centrosomal protein 164
Type
protein-coding
Aliases
NPHP15

This gene encodes a centrosomal protein involved in microtubule organization, DNA damage response, and chromosome segregation. The encoded protein is required for assembly of primary cilia and localizes to mature centrioles. Defects in this gene are a cause of nephronophthisis-related ciliopathies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012].

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Wikidata facts

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HomoloGene ID
51110
genomic end
117413266
genomic start
117185273
cytogenetic location
11q23.3
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Centrosomal protein of 164 kDa, also known as CEP164, is a protein that in humans is encoded by the CEP164 gene. Its function appears two be twofold: CEP164 is required for primary cilium formation. Furthermore, it is an important component in the response to DNA damage by UV light.

==References==

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