PIBF1
Sign in to saveAlso known as PIBF, C13orf24, CEP90, progesterone immunomodulatory binding factor 1, JBTS33
Progesterone-induced-blocking factor 1 is a protein that in humans is encoded by the PIBF1 gene. It has been shown to localize to the centrosome and has also been named CEP90.
Gene data
PIBF1- Name
- progesterone immunomodulatory binding factor 1
- Type
- protein-coding
- Position
- 72,781,641–73,017,823 (+)
- Aliases
- C13orf24, CEP90, JBTS33, PIBF
- Ensembl
- ENSG00000083535
- RefSeq RNA
- NM_001349655.2, NM_006346.4, NR_146205.2, NR_146206.2, XM_011534882.4
- RefSeq protein
- NP_001336584.1, NP_006337.2, XP_011533184.1, XP_011533186.1, XP_011533187.1
This gene encodes a protein that is induced by the steroid hormone progesterone and plays a role in the maintenance of pregnancy. The encoded protein regulates multiple facets of the immune system to promote normal pregnancy including cytokine synthesis, natural killer (NK) cell activity, and arachidonic acid metabolism. Low serum levels of this protein have been associated with spontaneous pre-term labor in humans. This protein may promote the proliferation, migration and invasion of glioma. [provided by RefSeq, Mar 2017].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Wikidata facts
Show 3 more facts
- HomoloGene ID
- 4628
- exact match
- identifiers.org/ncbigene/10464
- cytogenetic location
- 13q21.33-q22.1
Sources (3)
via Wikidata · CC0
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Article
3 sectionsContents
- References
- External links
- Further reading
Progesterone-induced-blocking factor 1 is a protein that in humans is encoded by the PIBF1 gene. It has been shown to localize to the centrosome and has also been named CEP90.
==References==