CEP350
Sign in to saveAlso known as CAP350, GM133, centrosomal protein 350
Centrosome-associated protein 350 is a protein that in humans is encoded by the CEP350 gene.
Gene data
CEP350- Name
- centrosomal protein 350
- Type
- protein-coding
- Position
- 179,954,674–180,114,880 (+)
- Aliases
- CAP350, GM133
- Ensembl
- ENSG00000135837
- RefSeq RNA
- NM_014810.5, XM_047435376.1, XM_047435377.1, XM_047435378.1, XM_047435382.1
- RefSeq protein
- NP_055625.4, XP_047291332.1, XP_047291333.1, XP_047291334.1, XP_047291338.1
The product of this gene is a large protein with a CAP-Gly domain typically found in cytoskeleton-associated proteins. The encoded protein primarily localizes to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. The encoded protein directly interacts with another large centrosomal protein and is required to anchor microtubules at the centrosome. It is also implicated in the regulation of a class of nuclear hormone receptors in the nucleus. Several alternatively spliced transcript variants have been found, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
centrosomal protein 350
- Symbol
- CEP350
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:179,954,674-180,114,880
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein CEP350 PDB 2coz.png
Show 7 more facts
- HomoloGene ID
- 8879
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/9857
- genomic end
- 180114875
- genomic start
- 179954773
- chromosome
- human chromosome 1
- cytogenetic location
- 1q25.2
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- External links
- Further reading
Centrosome-associated protein 350 is a protein that in humans is encoded by the CEP350 gene.
CEP350 is a large protein with a CAP-Gly domain typically found in cytoskeleton-associated proteins. It primarily localizes to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. CEP350 is required to anchor microtubules at the centrosome. Furthermore, it increases the stability of growing centrioles.
Excerpted from Wikipedia’s “CEP350” article, available under the CC BY-SA 4.0 licence.