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GeneQ18034631· pop 5· linked from 35 articles

CCP110

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Also known as CP110, Cep110, centriolar coiled-coil protein 110kDa, centriolar coiled-coil protein 110

Centriolar coiled-coil protein of 110 kDa also known as centrosomal protein of 110 kDa or CP110 is a protein that in humans is encoded by the CCP110 gene. It is a cell cycle-dependent CDK substrate and regulates centrosome duplication. CP110 suppresses a cilia assembly program.

Gene data

CCP110
Name
centriolar coiled-coil protein 110
Type
protein-coding
Position
19,523,808–19,553,408 (+)
Aliases
CP110, Cep110
Ensembl
ENSG00000103540
RefSeq RNA
NM_001199022.3, NM_001323569.2, NM_001323570.2, NM_001323571.2, NM_001323572.2
RefSeq protein
NP_001185951.2, NP_001310498.1, NP_001310499.1, NP_001310500.1, NP_001310501.1

Involved in centriole replication; negative regulation of cilium assembly; and regulation of cytokinesis. Located in centriole and centrosome. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022]

Gene Ontology

Pathways

Signal TransductionCell CycleOrganelle biogenesis and maintenanceSignaling by Rho GTPasesRegulation of PLK1 Activity at G2/M TransitionLoss of Nlp from mitotic centrosomesRecruitment of mitotic centrosome proteins and complexesLoss of proteins required for interphase microtubule organization from the centrosomeCentrosome maturationRecruitment of NuMA to mitotic centrosomes

via MyGene.info

Gene · Ensembl

centriolar coiled-coil protein 110

Symbol
CCP110
Biotype
Protein coding
Organism
Homo sapiens
Location
16:19,523,808-19,553,408
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Show 8 more facts
HomoloGene ID
8810
found in taxon
Homo sapiens
exact match
identifiers.org/ncbigene/9738
chromosome
human chromosome 16
genomic start
19535133
genomic end
19564730
cytogenetic location
16p12.3
expressed in
subthalamic nucleus
Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

3 sections
Contents
  • References
  • External links
  • Further reading

Centriolar coiled-coil protein of 110 kDa also known as centrosomal protein of 110 kDa or CP110 is a protein that in humans is encoded by the CCP110 gene. It is a cell cycle-dependent CDK substrate and regulates centrosome duplication. CP110 suppresses a cilia assembly program.

==References==

Excerpted from Wikipedia’s “CCP110” article, available under the CC BY-SA 4.0 licence.

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