CHRM1

Name

cholinergic receptor muscarinic 1

Type

protein-coding

Position

62,908,679–62,921,877 (−)

Aliases

HM1, M1, M1R

Ensembl

ENSG00000168539

RefSeq RNA

NM_000738.3, XM_011544742.3, XM_054367566.1

RefSeq protein

NP_000729.2, XP_011543044.1, XP_054223541.1

The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13. [provided by RefSeq, Jul 2008].

via MyGene.info

Wikidata facts

Image

Muscarinic receptor M1 coupled to protein G - 6OIJ.png

via Wikidata · CC0