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GeneQ18032349· pop 7· linked from 5 articles

Also known as CLIP, CLIP-115, CYLN2, WBSCR3, WBSCR4, WSCR3, WSCR4, CAP-Gly domain containing linker protein 2

CAP-Gly domain-containing linker protein 2 is a protein that in humans is encoded by the CLIP2 gene.

Gene data

CLIP2
Name
CAP-Gly domain containing linker protein 2
Type
protein-coding
Aliases
CLIP, CLIP-115, CYLN2, WBSCR3, WBSCR4, WSCR3, WSCR4

The protein encoded by this gene belongs to the family of cytoplasmic linker proteins, which have been proposed to mediate the interaction between specific membranous organelles and microtubules. This protein was found to associate with both microtubules and an organelle called the dendritic lamellar body. This gene is hemizygously deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008].

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Wikidata facts

Image
Protein CLIP2 PDB 2cp2.png
Show 5 more facts
HomoloGene ID
20718
genomic start
74289407
genomic end
74405935
cytogenetic location
7q11.23
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CAP-Gly domain-containing linker protein 2 is a protein that in humans is encoded by the CLIP2 gene.

The protein encoded by this gene belongs to the family of cytoplasmic linker proteins, which have been proposed to mediate the interaction between specific membranous organelles and microtubules. This protein was found to associate with both microtubules and an organelle called the dendritic lamellar body. This gene is hemizygously deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternative splicing of this gene generates 2 transcript variants.

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