TRIM3
Sign in to saveAlso known as BERP, HAC1, RNF22, RNF97, tripartite motif containing 3
Tripartite motif-containing protein 3 is a protein that in humans is encoded by the TRIM3 gene.
In the Vinony graph
Vinony's link graph records 4 inbound references to TRIM3, and connects out to PubMed, human chromosome 11 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 11.
Vinony links it to 5 Wikipedia language editions.
Gene data
TRIM3- Name
- tripartite motif containing 3
- Type
- protein-coding
- Position
- 6,448,613–6,474,459 (−)
- Aliases
- BERP, HAC1, RNF22, RNF97
- Ensembl
- ENSG00000110171
- RefSeq RNA
- NM_001248006.2, NM_001248007.2, NM_006458.4, NM_033278.4, NM_033279.1
- RefSeq protein
- NP_001234935.1, NP_001234936.1, NP_006449.2, NP_150594.2, XP_016872587.1
The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also called the 'RING-B-box-coiled-coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic filaments. It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class of myosins which are involved in the targeted transport of organelles. The rat protein can also interact with alpha-actinin-4. Thus it is suggested that this human protein may play a role in myosin V-mediated cargo transport. Alternatively spliced transcript variants encoding the same isoform have been identified. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
tripartite motif containing 3
- Symbol
- TRIM3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:6,448,613-6,474,459
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 21290
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/10612
- chromosome
- human chromosome 11
- genomic start
- 6469843
- genomic end
- 6495689
- cytogenetic location
- 11p15.4
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Interactions
- References
- Further reading
Tripartite motif-containing protein 3 is a protein that in humans is encoded by the TRIM3 gene.
The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also called the 'RING-B-box-coiled-coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic filaments. It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class of myosins which are involved in the targeted transport of organelles. The rat protein can also interact with alpha-actinin-4. Thus it is suggested that this human protein may play a role in myosin V-mediated cargo transport. Alternatively spliced transcript variants encoding the same isoform have been identified.
Excerpted from Wikipedia’s “TRIM3” article, available under the CC BY-SA 4.0 licence.