EntityQ410237· pop 39· linked from 432 articles

clopidogrel

Clopidogrel, sold under the brand name Plavix and other names, is an antiplatelet medication used to reduce the risk of heart disease and stroke in those at high risk. It is also used together with aspirin in heart attacks and following the placement of a coronary artery stent (dual antiplatelet therapy). It is taken by mouth. Its effect starts about two hours after intake and lasts for five days.

Key facts

Drug.verifiedrevid: 460044539
Drug.image: Clopidogrel skeletal formula.svg
Drug.image_class: skin-invert-image
Drug.width: 200
Drug.alt: Skeletal formula
Drug.image2: Clopidogrel molecule ball from xtal.png
Drug.image_class2: bg-transparent
Drug.width2: 200
Drug.alt2: Ball-and-stick model clopidogrel
Drug.tradename: Plavix, Iscover, others
Drug.MedlinePlus: a601040
Drug.DailyMedID: Clopidogrel
Drug.pregnancy_AU: B1
Drug.routes_of_administration: By mouth
Drug.ATC_prefix: B01
Drug.ATC_suffix: AC04
Drug.legal_AU: S4
Drug.legal_UK: POM

via Wikipedia infobox

Article

14 sections

Contents

Medical uses
Adverse effects
Interactions
Pharmacology
Pharmacokinetics and metabolism
Pharmacogenetics
Mechanism of action
Society and culture
Economics
Names
Veterinary uses
References
Further reading
External links

Common side effects include headache, nausea, easy bruising, itching, and heartburn. More severe side effects include bleeding and thrombotic thrombocytopenic purpura. While there is no evidence of harm from use during pregnancy, such use has not been well studied. Clopidogrel is in the thienopyridine-class of antiplatelets. It works by irreversibly inhibiting a receptor called P2Y12 on platelets.