coagulation factor IX

Protein · UniProt

Coagulation factor IX

Gene

F9

Organism

Homo sapiens (Human)

Length

461 aa

Molecular mass

51,778 Da

Evidence

1: Evidence at protein level

Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa (PubMed:8295821, PubMed:2592373, PubMed:20121197, PubMed:20121198, PubMed:1730085, PubMed:19846852, PubMed:39880037)

• COMPLETED
  Are There Differences Between Carriers of Haemophilia A and B?Cliniques universitaires Saint-Luc- Université Catholique de Louvain · NCT05217992
• PHASE1COMPLETED
  Study of FVIIa Variant BAY86-6150 (B0189) in Subjects With Moderate or Severe Hemophilia Types A or B With or Without InhibitorsBayer · NCT01921855
• COMPLETED
  Study of Prophylaxis, ACtivity and Effectiveness (SPACE) in Hemophilia Patients Currently Treated With ADVATE or RIXUBISBaxalta now part of Shire · NCT02190149
• PHASE1/PHASE2COMPLETED
  Trial of AAV5-hFIX in Severe or Moderately Severe Hemophilia BCSL Behring · NCT02396342
• NACOMPLETED
  Gene Therapy for Chinese Hemophilia BInstitute of Hematology & Blood Diseases Hospital, China · NCT04135300
• PHASE1COMPLETED
  Safety and Mode of Action of a Single Dose and Multiple Doses of Long Acting Activated Recombinant Human Factor VII in Patients With Haemophilia A and BNovo Nordisk A/S · NCT00922792

via ClinicalTrials.gov

Wikidata facts

Instance of

protein

Subclass of

protein precursor

via Wikidata · CC0