coagulation factor V

Protein · UniProt

Coagulation factor V

Gene

F5

Organism

Homo sapiens (Human)

Length

2,224 aa

Molecular mass

251,703 Da

Evidence

1: Evidence at protein level

Central regulator of hemostasis. It serves as a critical cofactor for the prothrombinase activity of factor Xa that results in the activation of prothrombin to thrombin

• Congenital coagulation factor V deficiency with intracranial hemorrhage.Journal of clinical laboratory analysis · 2022
• Coagulation factor V.The international journal of biochemistry & cell biology · 2004
• Coagulation factor V and thrombophilia: background and mechanisms.Thrombosis and haemostasis · 2007
• Coagulation factor V: an old star shines again.Thrombosis and haemostasis · 1997
• Cryo-EM structure of coagulation factor V short.Blood · 2023

via PubMed

• TERMINATED
  Identify Genetic Variations That Affect The Ability of Patients To Metabolize Drugs Through Metabolic PathwaysBracane Company · NCT02525887
• COMPLETED
  Prediction of Outcome in Severe PreeclampsiaCairo University · NCT03871764
• COMPLETED
  Study of Abnormal Blood Clotting in Children With StrokeNational Institute of Neurological Disorders and Stroke (NINDS) · NCT00001927
• COMPLETED
  Detection of Factor V Leiden G1691A and Factor II (Prothrombin) G20210A Point Mutations in DNAIllumina, Inc. · NCT00959504
• RECRUITING
  Engagement Study for Participants With Factor V Leiden and Prothrombin G20210A MutationsRichmond Research Institute · NCT07584265
• COMPLETED
  Assessment of the Prevalence of Major Psychiatric Disorders in a Cohort of Women With Clinical Criteria Corresponding to Pure, Abortive-form, Obstetrical, Antiphospholipid SyndromeCentre Hospitalier Universitaire de Nīmes · NCT02833194

via ClinicalTrials.gov