Carboxypeptidase B2
Sign in to saveAlso known as CPB2, thrombin-activable fibrinolysis inhibitor, Carboxypeptidase U, CPU, TAFI, carboxypeptidase B2 (plasma, carboxypeptidase U), carboxypeptidase R
mammalian protein found in Homo sapiens
Protein · UniProt
Carboxypeptidase B2
- Gene
- CPB2
- Organism
- Homo sapiens (Human)
- Length
- 423 aa
- Molecular mass
- 48,424 Da
- Evidence
- 1: Evidence at protein level
Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin
3D-structureAlternative splicingBlood coagulationCarboxypeptidaseDirect protein sequencingDisulfide bondFibrinolysisGlycoprotein
View on UniProt →
Swiss-Prot (reviewed) · via UniProt
Clinical Trials
1 registered- PHASE3RECRUITINGStudy of the Long-term Effects of P2Y12 Inhibitor Monotherapy and Coagulation Markers After Percutaneous Coronary Angioplasty.Cardiocentro Ticino · NCT07582835
Wikidata facts
- Instance of
- protein
Show 3 more facts
- cell component
- extracellular exosome
- biological process
- fibrinolysis
- found in taxon
- Homo sapiens
Sources (3)
via Wikidata · CC0