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fibrinolysis
EntityQ1410794· pop 20· linked from 449 articles

fibrinolysis

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Also known as GO:0042730

Fibrinolysis is a process that prevents blood clots from growing and becoming problematic. Primary fibrinolysis is a normal body process, while secondary fibrinolysis is the breakdown of clots due to a medicine, a medical disorder, or some other cause.

Research

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Encyclopedic overview

7 sections
Contents
  • Physiology
  • Measurement
  • Role in disease
  • Pharmacology
  • Fibrinolytic enzymes
  • References
  • External links

Fibrinolysis is a process that prevents blood clots from growing and becoming problematic. Primary fibrinolysis is a normal body process, while secondary fibrinolysis is the breakdown of clots due to a medicine, a medical disorder, or some other cause.

In fibrinolysis, a fibrin clot, the product of coagulation, is broken down. Its main enzyme plasmin cuts the fibrin mesh at various places, leading to the production of circulating fragments that are cleared by other proteases or by the kidney and liver.

Excerpted from Wikipedia’s “fibrinolysis” article, available under the CC BY-SA 4.0 licence.

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