CPLX2
Sign in to saveAlso known as 921-L, CPX-2, CPX2, Hfb1, complexin 2
Complexin-2 is a protein that in humans is encoded by the CPLX2 gene.
In the Vinony graph
Within Vinony's link graph, CPLX2 is referenced by 2 other articles, and connects out to PubMed, human chromosome 5 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 5.
Its subject is documented across 7 Wikipedia language editions.
Gene data
CPLX2- Name
- complexin 2
- Type
- protein-coding
- Position
- 175,796,306–175,884,022 (+)
- Aliases
- 921-L, CPX-2, CPX2, Hfb1
- Ensembl
- ENSG00000145920
- RefSeq RNA
- NM_001008220.2, NM_006650.4, NM_032282.1, XM_005265798.2, XM_005265799.2
- RefSeq protein
- NP_001008221.1, NP_006641.1, XP_005265855.1, XP_005265856.1, XP_011532721.1
Proteins encoded by the complexin/synaphin gene family are cytosolic proteins that function in synaptic vesicle exocytosis. These proteins bind syntaxin, part of the SNAP receptor. The protein product of this gene binds to the SNAP receptor complex and disrupts it, allowing transmitter release. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
complexin 2
- Symbol
- CPLX2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:175,796,306-175,884,022
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 38212
- genomic end
- 175311023
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/10814
- genomic start
- 175223313
- expressed in
- postcentral gyrus
- chromosome
- human chromosome 5
- cytogenetic location
- 5q35.2
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- External links
- Further reading
Complexin-2 is a protein that in humans is encoded by the CPLX2 gene.
Proteins encoded by the complexin/synaphin gene family are cytosolic proteins that function in synaptic vesicle exocytosis. These proteins bind syntaxin, part of the SNAP receptor. The protein product of this gene binds to the SNAP receptor complex and disrupts it, allowing transmitter release. Two transcript variants encoding the same protein have been found for this gene.
Excerpted from Wikipedia’s “CPLX2” article, available under the CC BY-SA 4.0 licence.