TLX2
Sign in to saveAlso known as HOX11L1, NCX, T-cell leukemia homeobox 2, T cell leukemia homeobox 2
T-cell leukemia homeobox protein 2 is a protein that in humans is encoded by the TLX2 gene.
In the Vinony graph
Vinony's link graph records 812 inbound references to TLX2, and connects out to PubMed, human chromosome 2 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 2.
Vinony links it to 5 Wikipedia language editions.
Gene data
TLX2- Name
- T cell leukemia homeobox 2
- Type
- protein-coding
- Position
- 74,513,463–74,517,148 (+)
- Aliases
- HOX11L1, NCX
- Ensembl
- ENSG00000115297
- RefSeq RNA
- NM_001534.2, NM_016170.5
- RefSeq protein
- NP_057254.1
This gene is a member of an orphan homeobox-containing transcription factor family. Studies of the mouse ortholog have shown that the encoded protein is crucial for the development of the enteric nervous system; in humans, loss-of-function may play a role in tumorigenesis of gastrointestinal stromal tumors. [provided by RefSeq, May 2010].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
T cell leukemia homeobox 2
- Symbol
- TLX2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:74,513,463-74,517,148
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 7575
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/3196
- genomic start
- 74740590
- chromosome
- human chromosome 2
- genomic end
- 74517148
- cytogenetic location
- 2p13.1
- expressed in
- appendix
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Interactions
- References
- Further reading
T-cell leukemia homeobox protein 2 is a protein that in humans is encoded by the TLX2 gene.
== Interactions ==
Excerpted from Wikipedia’s “TLX2” article, available under the CC BY-SA 4.0 licence.