cyanocobalamin
Cyanocobalamin is a form of vitamin used to treat and prevent vitamin deficiency except in the presence of cyanide toxicity. The deficiency may occur in pernicious anemia, following surgical removal of the stomach, with fish tapeworm, or due to bowel cancer. It is given by mouth, by injection into a muscle, or as a nasal spray.
Key facts
- Drug.solubility
- 1/80
- Drug.sol_units
- g/ml
- Drug.image
- Cyanocobalamin-b12.png
- Drug.image_class
- skin-invert-image
- Drug.caption
- Skeletal formula
- Drug.image2
- Cyanocobalamin-from-xtal-3D-st-noH.png
- Drug.image_class2
- bg-transparent
- Drug.caption2
- Stick model of cyanocobalamin based on the crystal structure
- Drug.pronounce
- sye AN oh koe BAL a min
- Drug.tradename
- Cobolin-M, Depo-Cobolin, others
- Drug.MedlinePlus
- a604029
- Drug.DailyMedID
- Cyanocobalamin
Article
12 sectionsContents
- Medical use
- Use in food
- Side effects
- Chemistry
- Chemical reactions
- Production
- Metabolism
- In the cytosol
- In mitochondria
- Absorption and transport
- See also
- References
Cyanocobalamin is a form of vitamin used to treat and prevent vitamin deficiency except in the presence of cyanide toxicity. The deficiency may occur in pernicious anemia, following surgical removal of the stomach, with fish tapeworm, or due to bowel cancer. It is given by mouth, by injection into a muscle, or as a nasal spray.
Cyanocobalamin is generally well tolerated. Minor side effects may include diarrhea, nausea, upset stomach, and itchiness. Serious side effects may include anaphylaxis, and low blood potassium resulting in heart failure. Use is not recommended in those who are allergic to cobalt or have Leber's disease. No overdosage or toxicity has been reported. It is less preferred than hydroxocobalamin for treating vitamin deficiency because it has a slightly lower bioavailability. Some studies have shown it to possess an antihypotensive effect. Vitamin is an essential nutrient meaning that it cannot be made by the body but is required for life.