Structure via PubChem · Public domain (PubChem)
cycrimine
Sign in to saveAlso known as alpha-Cyclopentyl-alpha-phenyl-1-piperidinepropanol, Cicrimina, (+-)-Cycrimine, Cycriminum, Pagitane
Cycrimine (trade name Pagitane) is an anticholinergic drug used in the treatment of Parkinson's disease. It is an antagonist of muscarinic acetylcholine receptor M1.
Chemical data
- Formula
- C19H29NO
- Molecular weight
- 287.4 g/mol
- IUPAC name
- 1-cyclopentyl-1-phenyl-3-piperidin-1-ylpropan-1-ol
- SMILES
- C1CCN(CC1)CCC(C2CCCC2)(C3=CC=CC=C3)O
- InChIKey
- SWRUZBWLEWHWRI-UHFFFAOYSA-N
- XLogP
- 3.9
- Polar surface area
- 23.5 Ų
- H-bond donors
- 1
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1982
- Admin. routes
- oral
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 287.225
- Has use
- medication
Show 4 more facts
- chemical formula
- C₁₉H₂₉NO
- Commons category
- Cycrimine
- canonical SMILES
- C1CCN(CC1)CCC(C2CCCC2)(C3=CC=CC=C3)O
- World Health Organisation international non-proprietary name
- cycrimine
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Synthesis
- See also
- References
- External links
Cycrimine (trade name Pagitane) is an anticholinergic drug used in the treatment of Parkinson's disease. It is an antagonist of muscarinic acetylcholine receptor M1.
==Synthesis== class=skin-invert-image|thumb|center|500px|Cycrimine synthesis:
Excerpted from Wikipedia’s “cycrimine” article, available under the CC BY-SA 4.0 licence.