CYTH2
Sign in to saveAlso known as ARNO, CTS18, CTS18.1, PSCD2, PSCD2L, SEC7L, Sec7p-L, Sec7p-like
Cytohesin-2 is a protein that in humans is encoded by the CYTH2 gene.
In the Vinony graph
Vinony's link graph records 9 inbound references to CYTH2, and connects out to PubMed, human chromosome 19 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 19.
Vinony links it to 8 Wikipedia language editions.
Gene data
CYTH2- Name
- cytohesin 2
- Type
- protein-coding
- Position
- 48,469,203–48,482,314 (+)
- Aliases
- ARNO, CTS18, CTS18.1, PSCD2, PSCD2L, SEC7L, Sec7p-L, Sec7p-like, cytohesin-2
- Ensembl
- ENSG00000105443
- RefSeq RNA
- NM_004228.7, NM_017457.6, XM_006723472.3, XM_047439682.1, XM_047439683.1
- RefSeq protein
- NP_004219.3, NP_059431.1, XP_006723535.1, XP_047295638.1, XP_047295639.1
The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with ARF1, ARF3, and ARF6 and is 83% homologous to CYTH1. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
cytohesin 2
- Symbol
- CYTH2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:48,469,203-48,482,314
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein PSCD2 PDB 1pbv.png
Show 7 more facts
- HomoloGene ID
- 32116
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/9266
- genomic end
- 48985571
- genomic start
- 48469208
- chromosome
- human chromosome 19
- cytogenetic location
- 19q13.33
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Interactions
- References
- Further reading
Cytohesin-2 is a protein that in humans is encoded by the CYTH2 gene.
== Function ==
Excerpted from Wikipedia’s “CYTH2” article, available under the CC BY-SA 4.0 licence.
Available in 8 languages
via Wikidata sitelinks · CC0