CST2
Sign in to saveAlso known as cystatin SA
Cystatin-SA is a protein that in humans is encoded by the CST2 gene.
In the Vinony graph
Within Vinony's link graph, CST2 is referenced by 2 other articles, and connects out to PubMed, human chromosome 20 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 20.
Its subject is documented across 5 Wikipedia language editions.
Gene data
CST2- Name
- cystatin SA
- Type
- protein-coding
- Position
- 23,823,769–23,826,735 (−)
- Ensembl
- ENSG00000170369
- RefSeq RNA
- NM_001322.3
- RefSeq protein
- NP_001313.1
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a secreted thiol protease inhibitor found at high levels in saliva, tears and seminal plasma. [provided by RefSeq, Jul 2008].
Gene Ontology
Molecular function
via MyGene.info
Gene · Ensembl
cystatin SA
- Symbol
- CST2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 20:23,823,769-23,826,735
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- exact match
- identifiers.org/ncbigene/1470
- found in taxon
- Homo sapiens
- genomic end
- 23826729
- genomic start
- 23804406
- chromosome
- human chromosome 20
- cytogenetic location
- 20p11.21
- expressed in
- gonad
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- External links
- Further reading
Cystatin-SA is a protein that in humans is encoded by the CST2 gene.
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a secreted thiol protease inhibitor found at high levels in saliva, tears and seminal plasma.
Excerpted from Wikipedia’s “CST2” article, available under the CC BY-SA 4.0 licence.