CYTH3
Sign in to saveAlso known as ARNO3, GRP1, PSCD3, cytohesin 3, cytohesin-3
Cytohesin-3 is a protein that in humans is encoded by the CYTH3 gene.
In the Vinony graph
Vinony's link graph records 2 inbound references to CYTH3, and connects out to PubMed, human chromosome 7 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 7.
Vinony links it to 6 Wikipedia language editions.
Gene data
CYTH3- Name
- cytohesin 3
- Type
- protein-coding
- Position
- 6,148,751–6,272,677 (−)
- Aliases
- ARNO3, GRP1, PSCD3, cytohesin-3
- Ensembl
- ENSG00000008256
- RefSeq RNA
- NM_001367580.1, NM_001367581.1, NM_001367582.1, NM_004227.4
- RefSeq protein
- NP_001354509.1, NP_001354510.1, NP_001354511.1, NP_004218.1
This gene encodes a member of the PSCD (pleckstrin homology, Sec7 and coiled-coil domains) family. PSCD family members have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This encoded protein is involved in the control of Golgi structure and function, and it may have a physiological role in regulating ADP-ribosylation factor protein 6 (ARF) functions, in addition to acting on ARF1. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
cytohesin 3
- Symbol
- CYTH3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:6,148,751-6,272,677
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein PSCD3 PDB 1bc9.png
Show 8 more facts
- HomoloGene ID
- 3116
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/9265
- genomic end
- 6312275
- genomic start
- 6201407
- chromosome
- human chromosome 7
- cytogenetic location
- 7p22.1
- expressed in
- tibia
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Cytohesin-3 is a protein that in humans is encoded by the CYTH3 gene.
This gene encodes a member of the cytohesin (CYTH) family, formerly known as the PSCD (pleckstrin homology, Sec7 and coiled-coil domains) family. Cytohesin family members have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of CYTHs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This encoded protein is involved in the control of Golgi structure and function, and it may have a physiological role in regulating ADP-ribosylation factor protein 6 (ARF) functions, in addition to acting on ARF1.
Excerpted from Wikipedia’s “CYTH3” article, available under the CC BY-SA 4.0 licence.